Attenuation of murine coronavirus infection by ammonium chloride
نویسندگان
چکیده
منابع مشابه
Receptor-independent infection of murine coronavirus: analysis by spinoculation.
A highly neurovirulent murine coronavirus JHMV (wild-type [wt] JHMV) is known to spread from cells infected via the murine coronavirus mouse hepatitis virus receptor (MHVR) to cells without MHVR (MHVR-independent infection), whereas a mutant virus isolated from wt JHMV, srr7, spread only in an MHVR-dependent fashion. These observations were obtained by the overlay of JHMV-infected cells onto re...
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Mouse hepatitis virus (MHV) infection spreads from MHV-infected DBT cells, which express the MHV receptor CEACAM1 (MHVR), to BHK cells, which are devoid of the receptor, by intercellular membrane fusion (MHVR-independent fusion). This mode of infection is a property of wild-type (wt) JHMV cl-2 virus but is not seen in cultures infected with the mutant virus JHMV srr7. In this study, we show tha...
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Large doses of KCI lowered serum uric acid while producing mild, apparently unrelated, uricosuria in four chlorothiazide-treated subjects. In two control subjects KCI also caused mild uricosuria, but had a negligible effect on serum uric acid concentration. Ammonium chloride decreased serum urate in all six subjects, while urinary uric acid excretion remained essentially unchanged. It is sugges...
متن کامل(1-Naphthylmethyl)ammonium chloride
The reaction of 1-naphthyl-methyl-amine and hydro-chloric acid in a 1:1 molar ratio resulted in the formation of the 1:1 proton-transfer compound, C(11)H(12)N(+)·Cl(-). In the crystal, the ions are linked by N-H⋯Cl hydrogen bonds into a sheet pattern in the ab plane such that each Cl(-) ion is bonded to three NH groups from the naphthylmethylammonium ion.
متن کامل(Methyldiphenylphosphoranylidene)ammonium chloride
The title compound, C(13)H(15)NP(+)·Cl(-), was obtained by hydrolysis of the N-trimethysilyl derivative of methydiphenyl-imino-phosphine. The dihedral angle between the phenyl rings in the cation is 61.5 (3)°. In the crystal structure, inter-molecular N-H⋯Cl hydrogen bonds links the two components, forming a centrosymmetric 2 + 2 aggregate.
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ژورنال
عنوان ژورنال: Virology
سال: 1985
ISSN: 0042-6822
DOI: 10.1016/0042-6822(85)90345-9